RNA interference-mediated simultaneous silencing of four genes using cross-shaped RNA
نویسندگان
چکیده
منابع مشابه
Using RNA interference to identify genes required for RNA interference.
RNA interference (RNAi) is a phenomenon in which double-stranded RNA (dsRNA) silences endogenous gene expression. By injecting pools of dsRNAs into Caenorhabditis elegans, we identified a dsRNA that acts as a potent suppressor of the RNAi mechanism. We have used coinjection of dsRNAs to identify four additional candidates for genes involved in the RNAi mechanism in C. elegans. Three of the gene...
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ژورنال
عنوان ژورنال: Molecules and Cells
سال: 2013
ISSN: 1016-8478,0219-1032
DOI: 10.1007/s10059-013-2316-7